Project status: Terminated

Coordinator: IRCCS ICS Maugeri, Pavia (IT)

Field: Oncology

Funded by: Regione Lombardia

Start date: 01 January 2010

Platform: i2b2


ONCO-i2b2 is a research project of the University of Pavia and IRCCS ICS Maugeri of Pavia to support clinical research in oncology. ONCO-i2b2, funded by Regione Lombardia, adopts the i2b2 software. Using i2b2 and new software modules specifically designed during the project, data from multiple sources have been integrated to allow cross-querying. The core of the integration process lies in the retrieval and fusion of data from the biobank management software and the ICS hospital information system. The integration process is based on an oncology domain ontology and open-source software integration modules. A Text-Mining/NLP (Natural Language Processing) module has also been implemented. This module automatically extracts clinical information of oncology patients from unstructured reports from Anatomy Pathology. The system handles more than two thousand patients.


Segagni D, Tibollo V, Dagliati A, Zambelli A, Priori SG, Bellazzi R (2012) An ICT infrastructure to integrate clinical and molecular data in oncology research. BMC Bioinformatics 13(Suppl 4): S5. (link, pdf)

Segagni D, Tibollo V, Dagliati A, Malovini A, Zambelli A, Napolitano C, Priori SG, Bellazzi R. Clinical and research data integration: the i2b2-FSM experience. AMIA Jt Summits Transl Sci Proc. 2013 Mar 18;2013:239-40. eCollection 2013. (link)

Segagni D, Tibollo V, Dagliati A, Perinati L, Zambelli A, Priori S, Bellazzi R. The ONCO-I2b2 project: integrating biobank information and clinical data to support translational research in oncology. Stud Health Technol Inform. 2011;169:887-91. (link, pdf)

Segagni D, Gabetta M, Tibollo V, Zambelli A, Priori SG, Bellazzi R. ONCO-i2b2: Improve patients selection through case-based information retrieval techniques. 8th International Conference on Data Integration in the Life Sciences, DILS 2012 (link)